منابع مشابه
Dmd053017 141..152
Ticlopidine is a first-generation thienopyridine antiplatelet drug that prevents adenosine 59-diphosphate (ADP)-induced platelet aggregation. We identified the enzymes responsible for the two-step metabolic bioactivation of ticlopidine in human liver microsomes and plasma. Formation of 2-oxo-ticlopidine, an intermediate metabolite, was NADPH dependent and cytochrome P450 (CYP) 1A2, 2B6, 2C19, a...
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A four year-old-girl with Diamond-Blackfan anemia (DBA) that was resistant to corticosteroid treatment and transfusion dependent underwent (bone marrow transplantation) BMT from HLA identical sibling. The patient was conditioned with busulfan and cyclophosphamide and achieved complete marrow engraftment and mixed chimerism in DNA analysis. For the following 13 months she was not transfusion dep...
متن کامل141-162 IPS_102433.indd
The literature on labor politics explains cooperation among unions, employers and state representatives in new democracies as a function of alliances between politically infl uential unions and left governments. This article introduces an original dataset of labor agreements in new democracies (1994–2004). Using Boolean analysis, it shows that while left governments are typically associated wit...
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Unsaturated fatty acids are ligands of PPAR-g , which up-regulates genes involved in fatty acid transport and TAG synthesis and the insulin-sensitising adipokine adiponectin, which activates fatty acid b-oxidation via PPAR-a action in liver. We investigated the effect of dietary fatty acid interaction with PPARG, PPARA and ADIPOQ gene variants on plasma lipid and adiponectin concentrations in t...
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Red blood cell (RBC) transfusions for massive hemorrhage induce systemic ischemic-reperfusion and influence the disposition and pharmacological activity of drugs as a result of a reduction in the level of expression and activity of cytochrome P450s (P450). It was reported that, when organ-preserving solutions are exposed to carbon monoxide (CO), the treatment was effective in suppressing the po...
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ژورنال
عنوان ژورنال: Plastic and Reconstructive Surgery - Global Open
سال: 2020
ISSN: 2169-7574
DOI: 10.1097/01.gox.0000667620.54888.9c